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Chromosomes in human beings can be divided into two styles: autosomes (body chromosome(s)) and allosome (intercourse chromosome(s)). Figure 1. Nondisjunction occurs when homologous chromosomes or sister chromatids fail to individual through meiosis, resulting in an abnormal chromosome number. Nondisjunction can come about in the course of both meiosis I or II, with differing final results (Figure 1). If homologous chromosomes are unsuccessful to separate throughout meiosis I, the consequence is two gametes that lack that unique chromosome and two gametes with two copies of the chromosome. 2. Nondisjunction happening during meiosis II benefits in 50 p.c typical gametes. If sister chromatids fail to independent for the duration of meiosis II, the end result is just one gamete that lacks that chromosome, two ordinary gametes with 1 duplicate of the chromosome, and a single gamete with two copies of the chromosome. Polyploid animals are sterile due to the fact meiosis simply cannot commence ordinarily and alternatively makes mostly aneuploid daughter cells that are not able to produce practical zygotes. Asexually reproducing species have one particular established of chromosomes that are the same in all system cells. The loops of 30-nm chromatin fibers are considered to fold on them selves even more to kind the compact metaphase chromosomes of mitotic cells. This remarkably compact type helps make the unique chromosomes noticeable, and they type the common 4-arm framework, a pair of sister chromatids hooked up to each and every other at the centromere