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HIV can enter the macrophage through binding of gp120 to CD4 and second membrane receptor, CCR5 (a chemokine receptor). T cells, although susceptibility to HIV infection differs among the macrophage subtypes. Brucella spp. can continue to be latent in a macrophage through inhibition of phagosome-lysosome fusion leads to brucellosis (undulant fever). Macrophages can impact treatment method outcomes both positively and negatively. Unnecessary treatment options improve charges and can result in sufferers pointless nervousness. American Journal of Respiratory and Critical Care Medicine. Journal of Leukocyte Biology. International Journal of Molecular Sciences. Hirayama D, Iida T, Nakase H (December 2017). "The Phagocytic Function of Macrophage-Enforcing Innate Immunity and Tissue Homeostasis". Littleton, Cynthia (August 8, 2017). "David Letterman to Host Netflix Interview Series". Hesketh M, Sahin KB, West ZE, Murray RZ (July 2017). "Macrophage Phenotypes Regulate Scar Formation and Chronic Wound Healing". 2004). Sherris Medical Microbiology (4th ed.). Aksnes, D. L. Nejstgaard, J. Sædberg, E. Sørnes, T. (2004). "Optical management of fish and zooplankton populations"

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